MyBioSource.com's PLOD3 Antibody (N-term) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PLOD3 Antibody (N-term) was generated using LH3, and PLOD3 as the antigen and it reacts with Human.
Description
The protein encoded by this gene is a membrane-bound
homodimeric enzyme that is localized to the cisternae of the rough
endoplasmic reticulum. The enzyme (cofactors iron and ascorbate)
catalyzes the hydroxylation of lysyl residues in collagen-like
peptides. The resultant hydroxylysyl groups are attachment sites
for carbohydrates in collagen and thus are critical for the
stability of intermolecular crosslinks. Some patients with
Ehlers-Danlos syndrome type VIB have deficiencies in lysyl
hydroxylase activity